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Dosage Form Information

Dosage forms are a mixture of active drug components and nondrug components. Depending on the method of administration they come in several types. These are liquid dosage form, solid dosage form and semisolid dosage forms. A Liquid dosage form is the liquid form of a dose of a chemical compound used as a drug or medication intended for administration or consumption. Common dosage forms include pill, tablet, or capsule, drink or syrup, (e.g., via oral ingestion or freebase smoking), and natural or herbal form such as plant or food of sorts, among many others. Notably, the route of administration (ROA) for drug delivery is dependent on the dosage form of the substance in question.

Various dosage forms may exist for a single particular drug, since different medical conditions can warrant different routes of administration. For example, persistent nausea and emesis or vomiting may make it difficult to use an oral dosage form, and in such a case, it may be necessary to utilize an alternate route such as inhalational, buccal, sublingual, nasal, suppository or parenteral instead.

Additionally, a specific dosage form may be a requirement for certain kinds of drugs, as there may be issues with various factors like chemical stability or pharmacokinetics. As an example, insulin cannot be given orally because upon being administered in this manner, it is extensively metabolized in the gastrointestinal tract (GIT) before reaching the blood stream, and is thereby incapable of sufficiently reaching its therapeutic target destinations. The oral and intravenous doses of a drug such as paracetamol will differ for the same reason.[1]

Types

Oral

Pastes(Colgate)

Inhalational

Parenteral Injection

Topical

Suppository

See also

References

  1. ^ http://www.bbc.co.uk/news/uk-scotland-glasgow-west-12366870

External links

Routes of administration / Dosage forms
Oral
Digestive tract (enteral)
Solids
Liquids
Buccal / Sublabial / Sublingual
Solids
Liquids
Respiratory tract
Solids
Liquids
Gas
Ocular / Otologic / Nasal
Urogenital
Rectal (enteral)
Dermal
Injection / Infusion (into tissue/blood)
Skin
Organs
Central nervous system
Circulatory / Musculoskeletal
Additional explanation:
Mucous membranes are used by the human body to absorb the dosage for all routes of administration, except for "Dermal" and "Injection/Infusion". Administration routes can also be grouped as Topical (local effect) or Systemic (defined as Enteral = Digestive tract/Rectal, or Parenteral = All other routes).
Routes of administration by organ system
Gastrointestinal Oral • BuccalSublabialSublingualRectal
Respiratory system Pulmonary • Nasal
Visual system / Auditory system Ocular (Ocular-topical / Intravitreal / Transscleral) • Otologic (Oto-topical)
Reproductive system Intracavernous • Intravaginal • Intrauterine (Extra-amniotic)
Urinary system Intravesical
Peritoneum Intraperitoneal
Central nervous system Intracerebral • IntrathecalEpidural
Circulatory system IntravenousIntracardiac
Musculoskeletal system IntramuscularIntraosseous
Skin Epicutaneous • IntradermalSubcutaneous

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from: Wiktionary: dosage form,
Sat Jan 7 11:10:40 2012