In chemistry, paraffin is a term that can be used synonymously with "alkane", indicating hydrocarbons with the general formula C_nH_2n+2. Paraffin wax refers to a mixture of alkanes that falls within the 20 ≤ n ≤ 40 range; they are found in the solid state at room temperature and begin to enter the liquid phase past approximately 37°C.

The simplest paraffin molecule is that of methane, CH₄, a gas at room temperature. Heavier members of the series, such as octane, C₈H₁₈, and mineral oil appear as liquids at room temperature. The solid forms of paraffin, called paraffin wax, are from the heaviest molecules from C₂₀H₄₂ to C₄₀H₈₂. Paraffin wax was identified by Carl Reichenbach in 1830.

Paraffin, or paraffin hydrocarbon, is also the technical name for an alkane in general, but in most cases it refers specifically to a linear, or normal alkane — whereas branched, or isoalkanes are also called isoparaffins. It is distinct from the fuel known in the United Kingdom, Ireland and South Africa as paraffin oil or just paraffin, which is called kerosene in most of the U.S., Canada, Australia and New Zealand.

The name is derived from Latin parum ("barely") + affinis, meaning "lacking affinity" or "lacking reactivity" indicating paraffin's unreactive nature )